A Patented Strain with Proof You Can Trust.
Unique-IS2 is one of the most studied Bacillus Coagulans globally, trusted by leading brands because the science is clear, consistent, and credible


Why Unique IS-2?
The Unique Advantage
Flexible use across formats
Easy integration into your NPD pipeline

Safe for consumption
Proven with in silico, in vitro, preclinical studies and clinical trials

Safe for consumption
Proven with in silico, in vitro, preclinical studies and clinical trials

Clear, marketable benefits
Backed by real human studies

Clear, marketable benefits
Backed by real human studies

High Stability and Survivability
No microencapsulation needed (Cost-effective)

High Stability and Survivability
No microencapsulation needed (Cost-effective)
Broad temperature range resistance
High boiling to low freezing temperatures
How it works
A Simple, Effective Mechanism
Unique-IS2 is designed to survive the journey through the digestive system and deliver benefits where they matter most.

Gram-positive, rod-shaped spore-forming bacterium

01
Ingestion
Unique IS-2 spores enter the GI tract upon oral consumption.
01
Ingestion
Unique IS-2 spores enter the GI tract upon oral consumption.
02
Activation
The spores activate in the stomach due to low pH and natural churning.
02
Activation
The spores activate in the stomach due to low pH and natural churning.
03
Germination
Active spores reach the intestine and begin to multiply.
03
Germination
Active spores reach the intestine and begin to multiply.
04
Action
They produce L(+)-lactic acid and other SCFAs that help lower pH and limit harmful bacteria.
04
Action
They produce L(+)-lactic acid and other SCFAs that help lower pH and limit harmful bacteria.
05
Enzyme Support
They release enzymes that help digest carbs, proteins, and fats.
05
Enzyme Support
They release enzymes that help digest carbs, proteins, and fats.
06
Clearance
The spores exit naturally within ~7 days after cessation of intake.
06
Clearance
The spores exit naturally within ~7 days after cessation of intake.
Clinical Studies
Proven Benefits. Backed by Studies.
Unique-IS2 has been studied across multiple health areas, with consistent outcomes that support clear, market-ready benefit positioning.
Explore by Benefit
Build Your Next Bestseller with Confidence
Get full access to all studies, technical data, and formulation guidance.

Build Your Next Bestseller with Confidence
Get full access to all studies, technical data, and formulation guidance.

Resources
Insights to Help You Build Better Products
Explore research updates, ingredient science, market trends, and formulation guidance designed for nutraceutical and food innovation teams.
