A Patented Strain with Proof You Can Trust.

Unique-IS2 is one of the most studied Bacillus Coagulans globally, trusted by leading brands because the science is clear, consistent, and credible

Why Unique IS-2?

The Unique Advantage

Flexible use across formats

Easy integration into your NPD pipeline

Safe for consumption

Proven with in silico, in vitro, preclinical studies and clinical trials

Safe for consumption

Proven with in silico, in vitro, preclinical studies and clinical trials

Clear, marketable benefits

Backed by real human studies

Clear, marketable benefits

Backed by real human studies

High Stability and Survivability

No microencapsulation needed (Cost-effective)

High Stability and Survivability

No microencapsulation needed (Cost-effective)

Broad temperature range resistance

High boiling to low freezing temperatures

How it works

A Simple, Effective Mechanism

Unique-IS2 is designed to survive the journey through the digestive system and deliver benefits where they matter most.

Gram-positive, rod-shaped spore-forming bacterium

01

Ingestion

Unique IS-2 spores enter the GI tract upon oral consumption.

01

Ingestion

Unique IS-2 spores enter the GI tract upon oral consumption.

02

Activation

The spores activate in the stomach due to low pH and natural churning.

02

Activation

The spores activate in the stomach due to low pH and natural churning.

03

Germination

Active spores reach the intestine and begin to multiply.

03

Germination

Active spores reach the intestine and begin to multiply.

04

Action

They produce L(+)-lactic acid and other SCFAs that help lower pH and limit harmful bacteria.

04

Action

They produce L(+)-lactic acid and other SCFAs that help lower pH and limit harmful bacteria.

05

Enzyme Support

They release enzymes that help digest carbs, proteins, and fats.

05

Enzyme Support

They release enzymes that help digest carbs, proteins, and fats.

06

Clearance

The spores exit naturally within ~7 days after cessation of intake.

06

Clearance

The spores exit naturally within ~7 days after cessation of intake.

Clinical Studies

Proven Benefits. Backed by Studies.

Unique-IS2 has been studied across multiple health areas, with consistent outcomes that support clear, market-ready benefit positioning.

Browse All
Gut Health
Women's Health
Immunity
Bone Health
Fitness
Overall Wellness
Weight Management
Oral Health

Build Your Next Bestseller with Confidence

Get full access to all studies, technical data, and formulation guidance.

Build Your Next Bestseller with Confidence

Get full access to all studies, technical data, and formulation guidance.

Resources

Insights to Help You Build Better Products

Explore research updates, ingredient science, market trends, and formulation guidance designed for nutraceutical and food innovation teams.